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Overview: Essential thrombocythemia is a Janus kinase 2 (JAK2) mutation-prevalent myeloproliferative neoplasm characterized by clonal thrombocytosis; clinical course is often。

The clinical picture is dominated by a predisposition to vascular occlusive events and hemorrhages. Some patients with ET are asymptomatic, while others may experience。

In patients with suspected ET who lack JAK2 and MPL mutations, the exclusion of reactive causes is particularly important ().In studies of。

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